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Image Search Results
Journal: PLoS ONE
Article Title: Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediatric Diffuse Intrinsic Pontine Gliomas
doi: 10.1371/journal.pone.0030313
Figure Lengend Snippet: Panel A: Radial plot showing the expression of oligodendroglial markers in the two groups of DIPG, in log2 ratios related each other. The red circle represent the median expression level of the whole population of DIPG. Group 1 expresses higher levels of oligodendroglial markers than group 2 DIPG. Panel B: Morphological oligodendroglial differenciation in group 1 tumors (HES staining, ×40). Panel C: Morphological astrocytic differenciation in group 2 tumors (HES staining ×40). Panel D: Olig2 immunohistochemistry in a group 1 DIPG showing that probably not all cells in the biopsy are tumoral (×40). Panel E: Dual immunohistochemistry for Olig2 and GFAP showing that tumor cells in mitosis are GFAP negative but Olig2 positive (×100). Panel F: Overall survival of 55 DIPG according to the presence (red) or absence (blue) of oligodendroglial differenciation. Median OS was shorter in patients with oligodendroglial type of tumors (7.73 vs 12.37, p = 0.045, log rank test).
Article Snippet: Sections were then incubated with various commercial
Techniques: Expressing, Staining, Immunohistochemistry
Journal: STAR Protocols
Article Title: Utilizing mouse optic nerve crush to examine CNS remyelination
doi: 10.1016/j.xpro.2021.100796
Figure Lengend Snippet:
Article Snippet:
Techniques: Transduction, Virus, Recombinant, Sterility, Saline, Imaging, Positive Control, Software, Microscopy